Berberine 500 mg, 60 tablets

Berberine - helps maintain healthy blood sugar levels

Known for its powerful effects on various aspects of health, especially blood sugar control, berberine is a yellow compound found in the roots, stems, leaves, and bark of several plants. Berberine has a long history of use in traditional Chinese medicine, but modern science has discovered and confirmed its impressive benefits. So what do the scientific studies say about the potential health benefits of berberine? 

Benefits:

• Increased insulin sensitivity
• Promoting insulin production
• Regulates metabolism
• Increasing glycolysis or its breakdown
• Reducing the production of glucose in the liver
• Increasing the production of nitric oxide, which helps to widen the arteries
• Slowing down the absorption of carbohydrates from the intestines

Studies

When taken orally, berberine is swallowed and then transported into the bloodstream before entering the body's cells. It binds to several "molecular targets" (also known as cellular or tissue structures) inside cells and changes their function. This can be compared to the action of pharmaceutical drugs. (source)

Berberine has cholesterol-lowering effects, which can improve heart health. It also has the potential to help lower blood sugar - prevent type 2 diabetes - fight bacteria and aid digestion and may even help with weight loss. Berberine is one of the few supplements that studies have shown can be as effective as medications. (source)

Many studies show that berberine can significantly lower blood sugar levels in people with type 2 diabetes.

Some clinical trials also show that taking 500mg of berberine two to three times a day for two to three months can reduce glycated hemoglobin (HbA1c), fasting plasma glucose (FPG) and postprandial glucose (PPG). (source)

Studies have shown that it can cause significant weight loss and improve all kinds of health indicators. For example, in a three-month study, those who took 500 mg of berberine three times a day saw a remission of metabolic syndrome and a decrease in waist circumferences. (source)

In another study, 37 men and women with metabolic syndrome took 300 mg of berberine three times a day for three months. Participants lowered their body mass index (BMI) from 31.5 to 27.5. They also lost belly fat and noticed better overall health. Known for its antibacterial and anti-inflammatory properties, berberine can support the gut microbiome and keep it in balance. A healthy gut flora can affect many areas of our health.

H. pylori (Helicobacter pylori) are bacteria that can cause an infection in the stomach or duodenum (first part of the small intestine). This is the most common cause of peptic ulcer disease and can also cause inflammation and irritate the stomach lining. Evidence from recent studies has shown that berberine can effectively reduce and kill H. pylori in vitro, even in strains that tolerated multiple drugs.

Berberine may improve some metabolic characteristics in women with PCOS (polycystic ovary syndrome) hormonal disorders. It has been found that taking berberine can lower blood sugar, improve cholesterol and triglyceride levels, lower testosterone levels, and reduce waist-to-hip ratio in people with PCOS. (source)

Fertility: Although more research is needed, this compound is believed to provide benefits, including improved fertility and a lowered risk of metabolic complications associated with this condition. A study published in Clinical Endocrinology found that women who took berberine had a higher pregnancy rate than those who took the insulin-sensitizing drug metformin.

Increasing insulin sensitivity: Many women with PCOS tend to be insulin resistant, which means their cells don't respond well to insulin, so insulin and blood sugar levels may rise. Research shows that berberine may play a role in treating insulin resistance by increasing the body's production and activity of compounds known to help minimize insulin sensitivity. (source)

While berberine has been shown to have many health benefits, it's important to note that the evidence is still limited, and you should tell your doctor about any dietary supplement you are taking.